We offer high-quality, shRNA libraries based on your target gene list. These RNAi libraries can serve as powerful and cost-efficient tools for performing large-scale screens for genes involved in disease pathways, cell responses to drug treatment, developmental processes, and gene regulation.
Step 1) In silico shRNA prediction
Mirimus proprietary algorithm generates a list of shRNAs which are predicted to have the power to silence the gene of interest.
Step 2) In vitro validation
Mirimus proprietary assay assesses the gene silencing potency of those predicted shRNAs, generating a report with shRNA knock-down activities.
Step 3) Plasmids
The best shRNAs are delivered to the client in the form of lentiviral or retroviral plasmid backbones.